Publications

2022

• Temporal control of PDGFRa regulates the fibroblast-to-myofibroblast transition in wound healing. Yao L, Rathnakar BH, Kwon HR, Sakashita H, Kim JH, Rackley A, Tomasek JJ, Berry WL, Olson LE. Cell Reports. In Press.

2021

• Skeletal stem cell fate defects caused by Pdgfrb activating mutation. Kwon HR, Kim JH, Woods JP, Olson LE. Development 2021 148(23):dev199607
• The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1⁺ hematoendothelial progenitors. Nandadasa S, O’Donnell A, Murao A, Yamaguchi Y, Midura RJ, Olson L, Apte SS. Matrix Biology 2021 97:40-57

2020

• Mosaic mutant analysis identifies PDGFRa/PDGFRb as negative regulators of adipogenesis. Sun C, Sakashita H, Kim J, Tang Z, Upchurch GM, Yao L, Berry WL, Griffin TM, Olson LE. Cell Stem Cell 2020 26(5):707-721.e5
• Fibroblast-specific Stat1 deletion enhances the myofibroblast phenotype during tissue repair. Medley SC, Rathnakar BH, Georgescu C, Wren JD, Olson LE. Wound Repair and Regeneration 2020 28(4);448-459
• Dysregulated mesenchymal PDGFR-b drives kidney fibrosis. Buhl EM, Djudjaj S, Klinkenhammer BM, Ermert K, Puelles VG, Lindenmeyer MT, Cohen CD, He C, Borkham-Kamphorst E, Weiskirchen R, Denecke B, Trairatphisan P, Saez-Rodriguez J, Huber TB, Olson LE, Floege J, Boor P. EMBO Molecular Medicine 2020 12(3):e11021

2018

• Complementary Wnt sources regulate lymphatic vascular development via PROX1-dependent Wnt/b-catenin signaling. Cha B, Geng X, Mahamud MR, Zhang JY, Chen L, Kim W, Jho EH, Kim Y, Choi D, Dixon JB, Chen H, Hong YK, Olson L, Kim TH, Merrill BJ, Davis MJ, Srinivasan RS. Cell Reports 2018 25(3):571-584.e5

2017

• STAT1 modulates tissue wasting or overgrowth downstream from PDGFRb. He C, Medley SC, Kim J, Sun C, Kwon HR, Sakashita H, Pincu Y, Yao L, Eppard D, Dai B, Berry WL, Griffin TM, Olson LE. Genes & Development 2017 31(16):1666-1678
• PDGFRa controls the balance of stromal and adipogenic cells during adipose tissue organogenesis. Sun C, Berry WL, Olson LE. Development 2017 144(1):83-94
• Pigment epithelium-derived factor, a noninhibitory serine protease inhibitor, is renoprotective by inhibiting the Wnt pathway. He X, Cheng R, Park K, Benyajati S, Moiseyev G, Sun C, Olson LE, Yang Y, Eby BK, Lau K, Ma JX. Kidney International (2017) 91(3):642-657

2015

• PDGFRa signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity. Iwayama T, Steele C, Yao L, Dozmorov MG, Karamichos D, Wren JD, Olson LE. Genes & Development 2015 29(11):1106-19
• PDGFRb signalling regulates local inflammation and synergizes with hypercholesterolaemia to promote atherosclerosis. He C, Medley SC, Hu T, Hinsdale ME, Lupu F, Virmani R, Olson LE. Nature Communications 2015 6:7770
• Double minute amplification of mutant PDGF receptor a in a mouse glioma model. Zou H, Feng R, Huang Y, Tripodi J, Najfeld V, Tsankova NM, Jahanshahi M, Olson LE, Soriano P, Friedel RH. Scientific Reports 2015 5:8468
• Detrimental effects of duplicate reads and low complexity regions on RNA- and ChIP-seq data. Dozmorov MG, Adrianto I, Giles CB, Glass E, Glenn SB, Montgomery C, Sivils KL, Olson LE, Iwayama T, Freeman WM, Lessard CJ, Wren JD. BMC Bioinformatics 2015 16(13)

2013

• Involvement of PDGF in fibrosis and scleroderma: recent insights from animal models and potential therapeutic opportunities. Iwayama T, Olson LE. Current Rheumatology Reports 2013 15(2):304

2012

• Radial construction of an arterial wall. Greif DM, Kumar M, Lighthouse JK, Hum J, An A, Ding L, Red-Horse K, Espinoza FH, Olson L, Offermanns S, Krasnow MA. Developmental Cell 2012 23(3):482-93

2011

• PDGFRb signaling regulates mural cell plasticity and inhibits fat development. Olson LE, Soriano P. Developmental Cell 2011 20(6):815-26