- slide one
Scar tissue is formed as a byproduct of wound repair or inflammation. Healthy tissue (muscle, red) develops fibrosis when scar tissue (blue) restricts normal function.
- slide two
Collagen fibers (red, right) are the main component of connective tissue, for example in the submucosa of the intestine (left).
- slide three
The wound environment stimulates nearby cells to become myofibroblasts (green) and secrete collagen to help repair damage.
- slide four
Arteries and veins
The walls of arteries (left) and veins (right) are structurally and functionally distinct because of differences in their mural cells and connective tissue.
- slide five
The aorta is largest blood vessel and has a thick wall of mural cells (red) and collagen-secreting fibroblasts (green).
- slide six
Blood vessels are made of mural cells (orange) and endothelial cells (green). Our research focuses on the biology of mural cells.
- slide seven
Capillary networks (brown) have specialized mural cells called pericytes (blue). Scientists are beginning to understand the function of pericytes in health and diseases like fibrosis
Cardiovascular Biology Research Program
Oklahoma Medical Research Foundation
825 NE 13th Street, MS 45
Oklahoma City, OK 73104-5005
Lab: (405) 271-7390
Office: (405) 271-7535