- slide one
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Scar tissue
Scar tissue is formed as a byproduct of wound repair or inflammation. Healthy tissue (muscle, red) develops fibrosis when scar tissue (blue) restricts normal function.
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Collagen
Collagen fibers (red, right) are the main component of connective tissue, for example in the submucosa of the intestine (left).
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Damaged Skin
The wound environment stimulates nearby cells to become myofibroblasts (green) and secrete collagen to help repair damage.
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Arteries and veins
The walls of arteries (left) and veins (right) are structurally and functionally distinct because of differences in their mural cells and connective tissue.
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Aorta
The aorta is largest blood vessel and has a thick wall of mural cells (red) and collagen-secreting fibroblasts (green).
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Vascular network
Blood vessels are made of mural cells (orange) and endothelial cells (green). Our research focuses on the biology of mural cells.
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Pericytes
Capillary networks (brown) have specialized mural cells called pericytes (blue). Scientists are beginning to understand the function of pericytes in health and diseases like fibrosis
Contact | Olson Lab Cardiovascular Biology Research Program Oklahoma Medical Research Foundation 825 NE 13th Street, MS 45 Oklahoma City, OK 73104-5005 |
Telephone Lab: (405) 271-7390 Office: (405) 271-7535 Email: Lorin-Olson@omrf.org |
Postdoc Positions Available! [Link] |